Research Article
Mortality Predictors and Survival Analysis in Cervical Cancer Patients Treated with Brachytherapy: A Retrospective Study at RMCH
Issue:
Volume 10, Issue 4, December 2024
Pages:
56-65
Received:
20 November 2024
Accepted:
2 December 2024
Published:
19 December 2024
Abstract: Cervical cancer remains a significant health burden, particularly in low- and middle-income countries, where over 85% of cases occur. Bangladesh exhibits crude incidence and mortality rates of 10.2 and 6.1 per 100,000, respectively, highlighting the impact of cervical cancer. This retrospective study, conducted at Rajshahi Medical College Hospital, assessed 141 cervical cancer patients treated with brachytherapy between December 2016 and December 2020. The primary objective was to examine survival outcomes and associated mortality factors in relation to the stage of cervical cancer at diagnosis. The study revealed that 59 patients (42%) were alive at the time of analysis, of which 88% had achieved disease-free survival. Conversely, 35 patients (25%) were deceased, with advanced-stage disease being predominant among them. Renal failure was identified as the leading cause of death (37%). Results suggest that early-stage cervical cancer correlates with improved survival outcomes, underscoring the necessity of early detection and prompt treatment. Despite the curative potential of brachytherapy when combined with external beam radiotherapy and cisplatin-based chemotherapy, global disparities in access to brachytherapy hinder effective cervical cancer management, particularly in low-resource settings. Enhanced screening programs, vaccination efforts, and broader access to advanced treatment modalities, including brachytherapy, are critical in reducing cervical cancer-related mortality in low- and middle-income countries.
Abstract: Cervical cancer remains a significant health burden, particularly in low- and middle-income countries, where over 85% of cases occur. Bangladesh exhibits crude incidence and mortality rates of 10.2 and 6.1 per 100,000, respectively, highlighting the impact of cervical cancer. This retrospective study, conducted at Rajshahi Medical College Hospital,...
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Research Article
Hp(10) and Hp(0.07) Annual Average Dose Received by Industrial Facilities and Practices Using TLD Dosimeters Over the Last Ten Years in Madagascar
Issue:
Volume 10, Issue 4, December 2024
Pages:
66-73
Received:
3 December 2024
Accepted:
16 December 2024
Published:
30 December 2024
DOI:
10.11648/j.rst.20241004.12
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Abstract: Ionizing radiations are commonly used in several sectors in Madagascar, especially in industrial field which represents a significant number of exposed workers. To protect workers against the harmful effect of ionizing radiations, all workers are covered by a personal monitoring program. This study was carried out at the Dosimetry and Radioprotection Department of the National Institute of Nuclear Sciences and Technologies (INSTN-Madagascar) to determine the average annual equivalent doses received by workers in industrial facilities and practices using TLD dosimeters over the last 10 years. The HARSHAW 6600 reader and TLDs cards, type-100 dosimeter cards were used. For this study, only annual doses below the regulatory limits [20 mSv.y-1 for Hp(10) and 500 mSv.y-1 for Hp(0.07)] were taken into consideration during this study. On average, 450 workers from approximately 12 industrial facilities were monitored during this period. The number of workers in 2013 (562 workers) was the highest, when compared to other years. The Hp (10) and Hp (0.07) annual equivalent doses received by industrial facilities over the last 10 years vary respectively from (0.97 ± 0.18) mSv.y-1 to (1.99 ± 0,92) mSv.y-1 with an average value of (1.36 ± 0.57) mSv.y-1, and from (0.96 ± 0.16) mSv.y-1 to (2.03 ± 0.92) mSv.y-1 with an average value of (1.37 ± 0.56) mSv.y-1. It has been established that the industrial radiography practice has received the highest annual doses, it varies from (0.73 ± 0.11) mSv.y-1 to (3.59 ± 2.88) mSv.y-1 with an average value of (1.71 ± 0.99) mSv.y-1 for Hp (10), and from (0.70 ± 0.29) mSv.y-1 to (3.60) ± 2.83) mSv.y-1 with an average value of (1.72 ± 0.99) mSv.y-1 for Hp (0.07).
Abstract: Ionizing radiations are commonly used in several sectors in Madagascar, especially in industrial field which represents a significant number of exposed workers. To protect workers against the harmful effect of ionizing radiations, all workers are covered by a personal monitoring program. This study was carried out at the Dosimetry and Radioprotecti...
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,
Karim Md. Abdul
